Ohlmann Patrick, Kim Sang-Wook, Mintz Gary S, Pregowski Jerzy, Tyczynski Pawel, Maehara Akiko, Escolar Esteban, Fournadjieva Jana A, Pichard Augusto D, Satler Lowell F, Kent Kenneth M, Suddath William O, Waksman Ron, Weissman Neil J
Cardiovascular Research Institute/Medstar Research Institute, Washington Hospital Center, Washington, DC, USA.
Am J Cardiol. 2005 Dec 15;96(12):1631-5. doi: 10.1016/j.amjcard.2005.07.087. Epub 2005 Oct 28.
The long-term outcome of patients who present with an identified plaque rupture in a nonflow-limiting lesion is not well known. We retrospectively studied 17 consecutive patients in whom intravascular ultrasound identified plaque rupture in nonflow-limiting lesions (minimum lumen area >4.0 mm2) that were not treated with coronary intervention. After a mean follow-up of 43 +/- 25 months, events related to those lesions were 1 death (6%) of undetermined cause (6%) that occurred after 69 months, no myocardial infarction, and 2 revascularizations (12%) that occurred at 3 and 67 months. Overall, the cumulative rate of cardiac events was 18%.
出现非血流限制性病变中已确定斑块破裂的患者的长期预后尚不清楚。我们回顾性研究了17例连续患者，这些患者经血管内超声检查发现有非血流限制性病变（最小管腔面积>4.0 mm²）中的斑块破裂，且未接受冠状动脉介入治疗。平均随访43±25个月后，与这些病变相关的事件包括1例（6%）在69个月后原因不明的死亡（6%），无心肌梗死，以及2例（12%）分别在3个月和67个月时进行的血运重建。总体而言，心脏事件的累积发生率为18%。
