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白塞病患者左右心室的组织多普勒速度及其与C反应蛋白和同型半胱氨酸水平的关联

Tissue Doppler velocities of the right and left ventricles and their association with C-reactive protein and homocysteine levels in Behcet's disease.

作者信息

Topal Ergun, Ozdemir Ramazan, Aksoy Yüksel, Acikgoz Nusret, Ermis Necip, Sincer Isa, Akturk Erdal, Ozcan Bülent

机构信息

Inonu University, Faculty of Medicine, Turgut Ozal Medical Center, Department of Cardiology, Malatya, Turkey.

出版信息

Am J Cardiol. 2005 Dec 15;96(12):1739-42. doi: 10.1016/j.amjcard.2005.07.099. Epub 2005 Nov 2.

Abstract

In the present study, we aimed to investigate whether tissue Doppler imaging could provide more information than standard echocardiography about left and right ventricular functions and their relations to homocysteine and C-reactive protein (CRP) levels in the course of Behcet's disease (BD). In the right ventricle, patients with BD had lower early diastolic tricuspid annular velocity and early diastolic/late diastolic tricuspid annular velocity ratios than the control group. Mitral and tricuspid annular systolic velocities did not significantly differ; however, diastolic velocities were correlated with duration of the disease. In addition, early/late diastolic mitral annular velocity ratio and early/late diastolic tricuspid annular velocity ratios showed an inverse relation with ocular involvement, serum homocysteine, and CRP levels in patients with BD.

摘要

在本研究中,我们旨在探讨组织多普勒成像是否能比标准超声心动图提供更多关于白塞病(BD)病程中左、右心室功能及其与同型半胱氨酸和C反应蛋白(CRP)水平关系的信息。在右心室中,BD患者的舒张早期三尖瓣环速度以及舒张早期/舒张晚期三尖瓣环速度比值低于对照组。二尖瓣和三尖瓣环收缩速度无显著差异;然而,舒张速度与病程相关。此外,BD患者的舒张早期/舒张晚期二尖瓣环速度比值和舒张早期/舒张晚期三尖瓣环速度比值与眼部受累、血清同型半胱氨酸及CRP水平呈负相关。

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