Taeger K
Institut für Anästhesiologie, Klinikum, Universität Regensburg.
Unfallchirurg. 1992 Apr;95(4):185-8.
There is a close relationship between trauma of the pelvis, hemorrhagic shock, microcirculation disturbances and multiple organ failure. Of primary importance are the treatment of pain, early intubation, artificial ventilation, protection against heat loss and replacement of massive blood loss. Contrary to conventional volume replacement by electrolyte solutions, the author favors the administration of colloids, especially the new concept of "small volume resuscitation," i.e., the rapid infusion of a mixture of hypertonic saline solution and hyperoncotic dextran. Although there are limitations, the central venous and pulmonary arterial pressure reflect the volume balance of the circulation. The oxygen partial pressure of mixed venous blood, more or less reflecting the global oxygen supply state of the organism, can be measured only by means of a pulmonary artery catheter. The outcome depends greatly on optimization of the oxygen supply to a patient in shock whose oxygen needs are remarkably increased. Therapy should be aimed at keeping the arterial oxygen tension above 150 mmHg, increasing the cardiac index to 50% above normal, and stabilizing the hemoglobin concentration at an individually optimized value.
骨盆创伤、失血性休克、微循环障碍与多器官功能衰竭之间存在密切关系。首要的是疼痛治疗、早期插管、人工通气、防止热量散失以及大量失血的补充。与传统的用电解质溶液进行容量替代不同,作者倾向于给予胶体,特别是“小容量复苏”这一新概念,即快速输注高渗盐溶液和高渗右旋糖酐的混合物。尽管存在局限性,但中心静脉压和肺动脉压反映了循环的容量平衡。混合静脉血的氧分压或多或少反映了机体的整体氧供应状态,只能通过肺动脉导管进行测量。结果在很大程度上取决于对休克患者氧供应的优化,这类患者的氧需求显著增加。治疗应旨在使动脉氧分压保持在150 mmHg以上,将心脏指数提高至高于正常水平50%,并将血红蛋白浓度稳定在个体优化值。