Farhi David, Dupin Nicolas
Service de dermato-vénéréologie, pavilion Tarnier, hôpital Cochin, 75679 Paris.
Rev Prat. 2005 Oct 31;55(16):1747-50.
Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by Chlamydia trachomatis serotypes L1, L2, and L3. It is endemic in tropical areas, while seldom in industrialised countries. Since 2002, an outbreak of rectal LGV has been observed among men having sex with men, in Netherlands, France, and other countries of Western Europe. After an incubation period of 2 days to 2 months, LGV develops in three stages: ulcerated papule; inflammatory satellite lymph node and/or proctitis; chronic inflammatory complications (fistulas and sclerosis). Chlamydia trachomatis infection is confirmed by PCR and serovars is identified by RFLP of omp1 gene amplified by PCR. Recommended first line treatment is doxycycline for at least 21 days.
性病性淋巴肉芽肿（LGV）是一种由沙眼衣原体L1、L2和L3血清型引起的性传播感染。它在热带地区流行，而在工业化国家很少见。自2002年以来，在荷兰、法国和西欧其他国家，男男性行为者中观察到直肠LGV疫情。经过2天至2个月的潜伏期后，LGV发展为三个阶段：溃疡丘疹；炎性卫星淋巴结和/或直肠炎；慢性炎症并发症（瘘管和硬化）。通过PCR确认沙眼衣原体感染，并通过PCR扩增的omp1基因的RFLP鉴定血清型。推荐的一线治疗是强力霉素至少治疗21天。
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