Das D K, Pant C S, Chachra K L, Gupta A K
Institute of Cytology, Indian Council of Medical Research, New Delhi.
Acta Cytol. 1992 Jul-Aug;36(4):517-22.
Among 1,283 cases of thyroid lesions subjected to fine needle aspiration cytology (FNAC) over a period of two years, 8 cases (0.6%) were found to be having cytologic features consistent with tuberculous thyroiditis. The ages of the patients ranged from 14 to 65 years, with a median of 30. The male:female ratio was 4:4. Six cases clinically presented with solitary nodules of the thyroid and two cases as abscesses in the thyroid region. Three patients had concomitant cervical lymphadenopathy, and only two patients were known cases of tuberculosis on treatment. Ultrasonography, done in seven cases, confirmed solitary nodules in four; in one case the differentiation between an extrathyroid nodule and cystic isthmic nodule was difficult, and in the remaining two cases the lesions were found to be extrathyroid. Fine needle aspirates from thyroid swellings showed epithelioid granuloma with necrosis in five cases and necrosis without epithelioid granuloma in three cases. The number of cases positive for acid-fast bacilli in these two groups were two and three, respectively. Lymph node aspiration, done in three cases, revealed necrotic material in two; both were positive for acid-fast bacilli, and the third case showed epithelioid granuloma without necrosis.
在两年期间接受细针穿刺细胞学检查(FNAC)的1283例甲状腺病变中,发现8例(0.6%)具有与结核性甲状腺炎一致的细胞学特征。患者年龄在14至65岁之间,中位数为30岁。男女比例为4:4。6例临床上表现为甲状腺单发结节,2例表现为甲状腺区域脓肿。3例患者伴有颈部淋巴结病,只有2例是正在接受治疗的已知结核病病例。7例进行了超声检查,4例证实为单发结节;1例难以区分甲状腺外结节和囊性峡部结节,其余2例病变位于甲状腺外。甲状腺肿大的细针穿刺抽吸物显示,5例有上皮样肉芽肿伴坏死,3例有坏死但无上皮样肉芽肿。这两组中抗酸杆菌阳性的病例数分别为2例和3例。3例进行了淋巴结抽吸,2例显示坏死物质;两者抗酸杆菌均为阳性,第3例显示无坏死的上皮样肉芽肿。