Nakamura Y, Ohta Y, Itoh S, Haratake A, Nakano Y, Umeda A, Shima H, Tomoda N
Department of Pathology, St. Mary's Hospital, Kurume-shi, Japan.
Acta Cytol. 1992 Jul-Aug;36(4):559-62.
Cytologic, light and electron microscopic, and immunohistochemical studies were conducted on a case of elastofibroma. Aspiration cytology showed a characteristic "braidlike" or "fern leaf-like" structure. Immunohistochemically the accumulate was shown to be elastin. Transmission electron microscopy indicated electron-dense, granular aggregates surrounded by microfilaments and collagen, while scanning electron microscopy revealed balls with a ball-of-yarn-like structure consisting of small fibrils, probably of elastin. These structures are unique to this disease and useful for diagnosis.