胎盘部位滋养细胞肿瘤

Placental site trophoblastic tumor.

作者信息

Desai Sushama Rajaram, Dombale Vijay Dhundiraj, Jadhav Asha Jagdish

机构信息

Dept. of Pathology, KIMS, Karad.

出版信息

Indian J Pathol Microbiol. 2005 Oct;48(4):505-7.

PMID:16366112

Abstract

Placental site trophoblastic tumor is very rare. It is a gestational trophoblastic neoplasm which follows normal or molar pregnancy. It is usually confined to uterus & 15-20% behave in a malignant fashion. Clinically patients present with abnormal excessive bleeding or amenorrhoea. Though several trophoblastic lesions & tumors enter in the differential diagnosis, microscopically the diagnosis is usually straightforward in hysterectomy specimens. Hysterectomy is the treatment with or without chemotherapy. Progress after surgery should be monitored by placental lactogenic hormone.

摘要

胎盘部位滋养细胞肿瘤非常罕见。它是一种继发于正常妊娠或葡萄胎妊娠的妊娠滋养细胞肿瘤。通常局限于子宫，15% - 20%表现为恶性。临床上患者表现为异常的过多出血或闭经。尽管有几种滋养细胞病变和肿瘤需进行鉴别诊断，但在显微镜下，子宫切除标本的诊断通常很直接。子宫切除术是治疗方法，可联合或不联合化疗。术后进展情况应通过胎盘生乳素进行监测。