Chatterjee Pranab Kr, Bairagi Debasis, Roy Sudipta, Majumder Nilay Kr, Paul Ratish Ch, Bagchi Sunil Ch
Susrut Eye Foundation & Research Centre, Kolkata.
J Indian Med Assoc. 2005 Jul;103(7):397-8.
A comparative double-blind placebo-controlled clinical trial of a herbal eye drop (itone) was conducted to find out its efficacy and safety in 120 patients with computer vision syndrome. Patients using computers for more than 3 hours continuously per day having symptoms of watering, redness, asthenia, irritation, foreign body sensation and signs of conjunctival hyperaemia, corneal filaments and mucus were studied. One hundred and twenty patients were randomly given either placebo, tears substitute (tears plus) or itone in identical vials with specific code number and were instructed to put one drop four times daily for 6 weeks. Subjective and objective assessments were done at bi-weekly intervals. In computer vision syndrome both subjective and objective improvements were noticed with itone drops. Itone drop was found significantly better than placebo (p<0.01) and almost identical results were observed with tears plus (difference was not statistically significant). Itone is considered to be a useful drug in computer vision syndrome.
开展了一项针对一种草药眼药水（itone）的双盲安慰剂对照临床试验，以研究其对120例患有计算机视觉综合征患者的疗效和安全性。研究对象为每天连续使用计算机超过3小时，出现流泪、眼红、乏力、刺激感、异物感等症状，并有结膜充血、角膜丝状物和黏液体征的患者。120例患者被随机给予安慰剂、泪液替代物（泪液加）或带有特定编号的相同小瓶中的itone，并被指示每天滴4次，持续6周。每两周进行一次主观和客观评估。在计算机视觉综合征患者中，itone眼药水在主观和客观方面均有改善。发现itone眼药水明显优于安慰剂（p<0.01），泪液加的效果与之几乎相同（差异无统计学意义）。itone被认为是治疗计算机视觉综合征的一种有效药物。
