Weber Sharon M, Lee Fred T
Department of Surgery, University of Wisconsin Madison, WI 53792, USA.
Oncology (Williston Park). 2005 Oct;19(11 Suppl 4):27-32.
Three definitive treatment options are available for patients with hepatic tumors: hepatic resection, tumor ablation, and hepatic transplantation. Ablative techniques--including radiofrequency ablation (RFA) and cryoablation--have greatly improved physicians' ability to definitively treat patients with primary and secondary hepatic tumors. Both RFA and cryoablation are safe and well-tolerated, but the effectiveness for local tumor eradication depends on many factors, including tumor size, location, number, and type. The choice of ablation modality is based on user and institutional biases. Assessing outcome after ablation is difficult because few studies with good long-term follow-up have evaluated local recurrence, disease-free survival, and overall survival after ablation. This and other limitations make it difficult to draw meaningful conclusions.
肝切除、肿瘤消融和肝移植。消融技术——包括射频消融（RFA）和冷冻消融——极大地提高了医生对原发性和继发性肝肿瘤患者进行确定性治疗的能力。RFA和冷冻消融都安全且耐受性良好，但局部肿瘤根除的有效性取决于许多因素，包括肿瘤大小、位置、数量和类型。消融方式的选择基于使用者和机构的偏好。评估消融后的结果很困难，因为很少有长期随访良好的研究评估消融后的局部复发、无病生存期和总生存期。这个以及其他限制使得难以得出有意义的结论。
