为晚期膀胱移行细胞癌开发创新策略。
Developing innovative strategies for advanced transitional cell carcinoma of the bladder.
作者信息
Pollera Camillo F, Nelli Fabrizio
机构信息
Department of Medical Oncology, Presidio Ospedaliero Centrale di Belcolle, ASL di Viterbo, Strada Sammartinese snc, 01100, Viterbo, Italy.
出版信息
Expert Rev Anticancer Ther. 2006 Jan;6(1):83-92. doi: 10.1586/14737140.6.1.83.
Several improvements in the treatment of advanced transitional cell malignancies have been provided by clinical trials in the past 10 years. Nonetheless, there are conflicting results regarding the effect of perioperative chemotherapy of muscle-invasive disease and new cytotoxic agents in the metastatic setting. The authors will discuss the results of major clinical trials and examine developing targeted-oriented treatment strategies.
在过去10年里，临床试验为晚期移行细胞恶性肿瘤的治疗带来了多项改进。尽管如此，关于肌层浸润性疾病围手术期化疗以及转移性环境中新型细胞毒性药物的效果，仍存在相互矛盾的结果。作者将讨论主要临床试验的结果，并探讨正在发展的靶向治疗策略。
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