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对环孢素治疗有反应的斯威特综合征。

Sweet's syndrome responding to cyclosporin.

作者信息

Bourke J F, Berth-Jones J, Graham-Brown R A

机构信息

Department of Dermatology, Leicester Royal Infirmary, U.K.

出版信息

Br J Dermatol. 1992 Jul;127(1):36-8. doi: 10.1111/j.1365-2133.1992.tb14823.x.

DOI:10.1111/j.1365-2133.1992.tb14823.x
PMID:1637692
Abstract

We report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed.

摘要

我们报告了一例用环孢素4毫克/千克/天治疗有效的Sweet综合征病例。环孢素对多种皮肤病有效，虽然环孢素的免疫抑制作用主要归因于抑制T淋巴细胞增殖，但也已表明它会影响中性粒细胞和单核细胞的功能。本文讨论了环孢素在Sweet综合征中的可能作用机制。

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Sweet's syndrome responding to cyclosporin.对环孢素治疗有反应的斯威特综合征。
Br J Dermatol. 1992 Jul;127(1):36-8. doi: 10.1111/j.1365-2133.1992.tb14823.x.
2
Sweet's syndrome--therapy with cyclosporin.斯威特综合征——环孢素治疗
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Sweet's syndrome: a review of current treatment options.斯威特综合征：当前治疗选择综述
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Sweet syndrome secondary to inflammatory bowel disease.炎症性肠病继发的Sweet综合征
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Neutrophilic dermatoses: pyoderma gangrenosum and Sweet's syndrome.嗜中性皮病：坏疽性脓皮病和Sweet综合征。
Postgrad Med J. 1997 Feb;73(856):65-8. doi: 10.1136/pgmj.73.856.65.
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The cyclosporins.环孢菌素类
Folia Microbiol (Praha). 1995;40(1):68-88. doi: 10.1007/BF02816529.
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Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders.环孢素。对其药效学和药代动力学特性以及在免疫调节紊乱中的治疗应用的综述。
Drugs. 1993 Jun;45(6):953-1040. doi: 10.2165/00003495-199345060-00007.