[采用梯度回波序列对骨髓进行磁共振断层扫描筛查研究。II. 钆喷酸葡胺辅助的浆细胞瘤患者研究]

[Magnetic resonance tomographic screening studies of the bone marrow with gradient-echo sequences. II. Gadolinium-DTPA-supported studies of plasmocytoma patients].

作者信息

Hosten N, Schörner W, Neumann K, Sander B, Oertel J, Kirsch A, Schubeus P, Cordes M, Felix R, Huhn D

机构信息

Strahlenklinik und Poliklinik, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin.

出版信息

Rofo. 1992 Jul;157(1):53-8. doi: 10.1055/s-2008-1032965.

DOI:10.1055/s-2008-1032965

PMID:1638006

Abstract

MR imaging was performed in 19 patients with proven multiple myeloma. Both plain and Gd-DTPA enhanced in-phase and opposed-phase gradient-echo techniques were used (0.1 mmol Magnevist/kg body weight). Plain, opposed-phase imaging demonstrated more lesions than plain in-phase imaging (35 vs. 16); enhanced opposed-phase imaging demonstrated more lesions than plain opposed-phase and enhanced in-phase imaging (47 vs. 35 and 17 lesions). These results suggest that enhanced opposed-phase images which have a high contrast between normal and infiltrated bone marrow are especially suited for MR screening in multiple myeloma.

摘要

对19例确诊为多发性骨髓瘤的患者进行了磁共振成像（MR）检查。采用了普通及钆喷酸葡胺（Gd-DTPA）增强的同相位和反相位梯度回波技术（0.1 mmol钆喷酸葡胺/千克体重）。普通反相位成像显示的病灶比普通同相位成像更多（35个对16个）；增强反相位成像显示的病灶比普通反相位成像及增强同相位成像更多（47个对35个和17个病灶）。这些结果表明，正常骨髓与浸润骨髓之间具有高对比度的增强反相位图像特别适合于多发性骨髓瘤的MR筛查。