Sullivan James C, Ryan Joseph F, Watson James A, Webb Jeramy, Mullikin James C, Rokhsar Daniel, Finnerty John R
Department of Biology, Boston University, 5 Cummington Street, Boston, MA 02215, USA.
Nucleic Acids Res. 2006 Jan 1;34(Database issue):D495-9. doi: 10.1093/nar/gkj020.
StellaBase, the Nematostella vectensis Genomics Database, is a web-based resource that will facilitate desktop and bench-top studies of the starlet sea anemone. Nematostella is an emerging model organism that has already proven useful for addressing fundamental questions in developmental evolution and evolutionary genomics. StellaBase allows users to query the assembled Nematostella genome, a confirmed gene library, and a predicted genome using both keyword and homology based search functions. Data provided by these searches will elucidate gene family evolution in early animals. Unique research tools, including a Nematostella genetic stock library, a primer library, a literature repository and a gene expression library will provide support to the burgeoning Nematostella research community. The development of StellaBase accompanies significant upgrades to CnidBase, the Cnidarian Evolutionary Genomics Database. With the completion of the first sequenced cnidarian genome, genome comparison tools have been added to CnidBase. In addition, StellaBase provides a framework for the integration of additional species-specific databases into CnidBase. StellaBase is available at http://www.stellabase.org.
星状海葵基因组数据库(StellaBase)是一个基于网络的资源库,将有助于对星状海葵进行桌面研究和实验台研究。星状海葵是一种新兴的模式生物,已被证明有助于解决发育进化和进化基因组学中的基本问题。StellaBase允许用户使用基于关键词和同源性的搜索功能,查询已组装的星状海葵基因组、一个经过确认的基因文库和一个预测基因组。这些搜索提供的数据将阐明早期动物的基因家族进化。独特的研究工具,包括星状海葵遗传种群文库、引物文库、文献库和基因表达文库,将为蓬勃发展的星状海葵研究群体提供支持。StellaBase的开发伴随着刺胞动物进化基因组数据库(CnidBase)的重大升级。随着首个测序刺胞动物基因组的完成,基因组比较工具已被添加到CnidBase中。此外,StellaBase为将其他物种特异性数据库整合到CnidBase中提供了一个框架。可通过http://www.stellabase.org访问StellaBase。