Hayashi H, Toda T, Tabata T
Department of Physiology, School of Dentistry, Tohoku University, Sendai, Japan.
Brain Res. 1992 Mar 6;574(1-2):329-32. doi: 10.1016/0006-8993(92)90835-w.
Somatosensory neurons projecting to the mesencephalic parabrachial area (MPBA), which is located ventral to the inferior colliculus and dorsal to the brachium conjunctivum, were recorded from the bulbar reticular formation of adult cats anesthetized with alpha-chloralose. The majority (41 of 50 neurons) were nociceptive-specific neurons responding only to noxious mechanical and/or thermal stimuli to the skin, cornea and/or oral mucosa. The size of their receptive fields was smaller than that of the intrinsic MPBA-neurons, but larger than that of the trigeminal sensory nucleus neurons. Twenty-three neurons received input from the tooth pulp nerve and 10 of 32 neurons tested responded to electrical stimulation of the vagal nerve. These results indicate that these bulbar reticular neurons receive noxious inputs and transmit them to the MPBA, which also receives input from spinal or trigeminal sensory nucleus neurons projecting directly to the MPBA.
投射至中脑臂旁区（MPBA）的体感神经元被记录下来，该区域位于下丘下方、结合臂上方，实验对象是用α-氯醛糖麻醉的成年猫的延髓网状结构。大多数（50个神经元中的41个）是伤害性特异性神经元，仅对皮肤、角膜和/或口腔黏膜的有害机械和/或热刺激有反应。它们的感受野大小比MPBA固有神经元的小，但比三叉神经感觉核神经元的大。23个神经元接受来自牙髓神经的输入，32个接受测试的神经元中有10个对迷走神经的电刺激有反应。这些结果表明，这些延髓网状神经元接收有害输入并将其传递至MPBA，而MPBA也接收直接投射至MPBA的脊髓或三叉神经感觉核神经元的输入。
