Tuan Kuang-Mon Ashley, Chernyak Dimitri, Feldman Sandy T
VISX Inc, Santa Clara, California, USA.
Am J Ophthalmol. 2006 Jan;141(1):1-6. doi: 10.1016/j.ajo.2005.08.065.
To evaluate the accuracy of the diagnostic capabilities of optical metrics generated from wavefront measurements in relationship to post-laser-assisted in situ keratomileusis (LASIK) visual complaints as expressed and drawn by patients.
Retrospective analysis and observational case series.
Patient wavefront data from an investigational device exemption study for wavefront-guided ablations were used to derive normative modulation transfer function (MTF), encircled energy (EE), and Strehl ratio. These optical metrics and their point-spread functions (PSF) were compared with data from five postoperative patients with night vision complaints. Patients were asked to draw their symptoms, which were elicited by testing with a Fenthoff muscle light, while using their best-corrected distance vision.
The MTF, EE, and Strehl ratio of most patients were markedly different from those of the averages of 208 normal myopic eyes before and after LASIK surgery. The spatial extent of the PSF correlated positively with the severity of the visual complaints. Wavefront-derived PSFs were markedly similar to the patients' drawings.
The results of this study demonstrate the diagnostic capability of the wavefront system in predicting visual symptoms and complaints of patients with high-order aberrations. Objective visual metrics from patients with night vision complaints were different from those of normal myopic eyes that had undergone LASIK procedures.
评估基于波前测量得出的光学指标在诊断与患者表述及描绘的准分子激光原位角膜磨镶术（LASIK）术后视觉不适相关问题时的准确性。
回顾性分析和观察性病例系列研究。
来自一项波前引导消融的研究器械豁免研究的患者波前数据用于得出标准调制传递函数（MTF）、环围能量（EE）和斯特列尔比。将这些光学指标及其点扩散函数（PSF）与五名有夜间视力问题的术后患者的数据进行比较。要求患者在使用最佳矫正远视力的同时，描绘出在使用芬托夫肌肉灯测试时引发的症状。
大多数患者的MTF、EE和斯特列尔比与208只LASIK手术前后正常近视眼睛的平均值显著不同。PSF的空间范围与视觉不适的严重程度呈正相关。基于波前的PSF与患者的描绘明显相似。
本研究结果证明了波前系统在预测高阶像差患者视觉症状和不适方面的诊断能力。有夜间视力问题患者的客观视觉指标与接受LASIK手术的正常近视眼睛的指标不同。
