Jin George J C, Merkley Kevin H
The Eye Institute of Utah, Salt Lake City, Utah 84107, USA.
Am J Ophthalmol. 2006 Apr;141(4):660-8. doi: 10.1016/j.ajo.2005.11.011.
To assess the clinical outcomes of conventional and wavefront-guided myopic laser in situ keratomileusis (LASIK) retreatment.
Retrospective, nonrandomized case series.
The study comprised a cohort of 97 eyes having LASIK retreatment for residual myopia after primary LASIK. The eyes were divided into two groups: conventional retreatment (CR) group (n = 74) and wavefront-guided retreatment (WR) group (n = 23). The retreatment LASIK was performed using LADARVison 4000 with/without CustomCornea (Alcon Surgical, Orlando, Florida, USA). The mean follow-up was 8.9 +/- 5.8 months after retreatment (range three to thirty-six months).
The mean pre-retreatment spherical equivalent (SE) was -0.93 +/- 0.41 diopters in the CR group and -0.84 +/- 0.48 diopters in the WR group (P = .409). At the last visit, the mean SE was -0.19 +/- 0.28 diopters and +0.32 +/- 0.47 diopters, respectively (P < .001). An SE of +/- 0.50 diopters was achieved in 92% (68 of 74) of CR eyes and 65% (15 of 23) of WR eyes. In the CR group, 85% eyes had a uncorrected visual acuity (UCVA) > or = 20/20 and 99% > or = 20/40, and in the WR group, 35% and 100%, respectively. None of the CR eyes and 17% (4 of 23) of WR eyes lost two lines of best spectacle-corrected visual acuity (BSCVA). Nine percent (7 of 74) of CR eyes and 30% of WR eyes (7 of 23) had optical symptoms before retreatment, the number was reduced to 1% (1 of 74) and 4% (1 of 23), respectively.
In the study period with the current equipment, our results showed that conventional LASIK retreatment was superior to wavefront-guided LASIK retreatment in both efficacy and safety.
评估传统与波前像差引导的准分子原位角膜磨镶术（LASIK）再次手术的临床效果。
回顾性、非随机病例系列研究。
本研究纳入97只接受LASIK再次手术以矫正初次LASIK术后残余近视的眼睛。将这些眼睛分为两组：传统再次手术（CR）组（n = 74）和波前像差引导再次手术（WR）组（n = 23）。使用LADARVison 4000并搭配/不搭配CustomCornea（爱尔康手术公司，美国佛罗里达州奥兰多）进行再次手术LASIK。再次手术后平均随访时间为8.9±5.8个月（范围3至36个月）。
CR组再次手术前平均等效球镜度（SE）为-0.93±0.41屈光度，WR组为-0.84±0.48屈光度（P = 0.409）。在最后一次随访时，平均SE分别为-0.19±0.28屈光度和+0.32±0.47屈光度（P < 0.001）。CR组92%（74只中的68只）和WR组65%（23只中的15只）的眼睛达到±0.50屈光度的SE。CR组中，视力（UCVA）≥20/20的眼睛占85%，≥20/40的占99%；WR组中，这两个比例分别为35%和100%。CR组无眼睛，WR组17%（23只中的4只）的眼睛最佳矫正视力（BSCVA）下降两行。CR组9%（74只中的7只）和WR组30%（23只中的7只）在再次手术前有光学症状，再次手术后这一数字分别降至1%（74只中的1只）和4%（23只中的1只）。
在使用当前设备的研究期间，我们的结果表明，传统LASIK再次手术在疗效和安全性方面均优于波前像差引导的LASIK再次手术。
