Gallardo Mark J, Randleman J Bradley, Price Kristina M, Johnson Daniel A, Acosta Sharon, Grossniklaus Hans E, Stulting R Doyle
Department of Ophthalmology, University of Texas Health Sciences Center, San Antonio, TX, USA.
Am J Ophthalmol. 2006 Jan;141(1):198-200. doi: 10.1016/j.ajo.2005.07.054.
To report cases of ocular argyrosis that developed after long-term self-application of commercially available eyelash tint.
Observational case series.
Case review, clinicopathologic analysis, and literature review.
Three patients developed ocular argyrosis after the long-term self-application of Revlon Professional Roux Lash and Brow Tint (Colomer USA Corp, New York, New York, USA). Clinical evaluation revealed various degrees of silver deposition on the upper eyelid, lid margin, caruncle and conjunctiva, and diffuse Descemet's membrane deposits. In one case, histologic examination demonstrated silver deposition in the basement membrane and superficial substantia propria of the conjunctiva.
Argyrosis can occur after long-term application of readily available eyelash tints, and the deposition of silver may be permanent. In certain circumstances, conjunctival argyrosis may simulate benign and malignant lesions, including conjunctival melanoma. These products should only be applied by trained cosmetologists.
报告长期自行使用市售睫毛染色剂后发生眼部银质沉着症的病例。
观察性病例系列。
病例回顾、临床病理分析及文献复习。
3例患者在长期自行使用露华浓专业柔皙睫毛眉毛染色剂（美国纽约科洛默美国公司）后发生眼部银质沉着症。临床评估显示上睑、睑缘、泪阜和结膜有不同程度的银沉积，以及弥漫性Descemet膜沉积。1例病例的组织学检查显示结膜基底膜和浅层固有层有银沉积。
长期使用容易获得的睫毛染色剂可发生银质沉着症，且银沉积可能是永久性的。在某些情况下，结膜银质沉着症可能会模拟良性和恶性病变，包括结膜黑色素瘤。这些产品应由训练有素的美容师使用。
