Rahman Waheeda, Proudlock Frank, Gottlob Irene
Department of Ophthalmology, University Hospitals of Leicester, Leicester, United Kingdom.
Am J Ophthalmol. 2006 Jan;141(1):221-2. doi: 10.1016/j.ajo.2005.08.022.
To describe a patient with symptomatic Heimann-Bielschowsky phenomenon (HBP) treated successfully with oral gabapentin.
Interventional case report.
A 57-year-old patient with retinitis pigmentosa had a 12-month history of vertical oscillopsia. The right visual acuity was 20/200 and the left visual acuity was 20/60 with glasses. He had a coarse, slow, pendular, vertical movement of the right eye consistent with Heimann-Bielschowsky phenomenon. His treatment commenced with oral gabapentin with gradual increase in dose to 2400 mg/d. Eye movement recordings were performed before and after treatment.
He became considerably less symptomatic on gabapentin. The right visual acuity improved to 20/80 with glasses. Eye movement recordings confirmed markedly reduced vertical oscillations of the right eye. The patient continues on gabapentin with no side effects and sustained effect.
The vertical nystagmoid movement in HBP can be considerably reduced and symptoms remarkably improved when treated with oral gabapentin.
描述一名成功接受口服加巴喷丁治疗的有症状的海曼-比尔绍斯基现象（HBP）患者。
介入性病例报告。
一名57岁的视网膜色素变性患者有12个月的垂直性视振荡病史。右眼视力为20/200，左眼视力矫正后为20/60。他的右眼有粗大、缓慢、摆动性的垂直运动，符合海曼-比尔绍斯基现象。治疗从口服加巴喷丁开始，剂量逐渐增加至2400毫克/天。治疗前后进行了眼动记录。
服用加巴喷丁后他的症状明显减轻。右眼视力矫正后提高到20/80。眼动记录证实右眼的垂直振荡明显减少。患者继续服用加巴喷丁，无副作用且效果持续。
口服加巴喷丁治疗时，HBP中的垂直眼球震颤运动可显著减少，症状明显改善。
