Maisel Alan S, Bhalla Vikas, Braunwald Eugene
Department of Medicine, Veterans Affairs San Diego Healthcare System and University of California, San Diego, CA 92161, USA.
Nat Clin Pract Cardiovasc Med. 2006 Jan;3(1):24-34. doi: 10.1038/ncpcardio0405.
The field of cardiac biomarkers has grown by leaps and bounds in the past two decades. In this review we try to summarize the explosion of emerging knowledge and address the roles of some of the biomarkers that have either proven or potential utility. We detail some of the markers of ischemia, hemodynamic markers of heart failure, inflammatory markers, and the novel and innovative approach of combining these for a multimarker strategy. At the end of this review we highlight some of the biomarker-guided approaches and strategies that might lead to better and more-effective care of patients.
在过去二十年中,心脏生物标志物领域取得了飞速发展。在本综述中,我们试图总结新出现的知识的激增情况,并探讨一些已被证实或具有潜在效用的生物标志物的作用。我们详细介绍了一些缺血标志物、心力衰竭的血流动力学标志物、炎症标志物,以及将这些标志物结合起来用于多标志物策略的新颖创新方法。在本综述结尾,我们重点介绍了一些可能带来更好、更有效患者护理的生物标志物引导的方法和策略。