Wu Jashin J, Huang David B, Pang Katie R, Tyring Stephen K
Department of Dermatology, University of California, Irvine, California, USA.
J Cutan Med Surg. 2005 Apr;9(2):54-62. doi: 10.1007/s10227-005-0133-0.
The rickettsial diseases are an important group of infectious agents that have dermatological manifestations. These diseases are important to consider in endemic areas, but in certain suspicious cases, possible acts of bioterrorism should warrant prompt notification of the appropriate authorities.
In this two part review article, we review these diverse diseases by examining established and up-to-date information about the pathophysiology, epidemiology, clinical manifestations, and treatment of the ricksettsiae.
Using PubMed to search for relevant articles, we browsed over 500 articles to compose a clinically based review article.
Part one focuses on pathophysiology of the rickettsial diseases and the clinical aspects of the spotted fever group.
At the completion of part one of this learning activity, participants should be able to discuss all of the clinical manifestations and treatments of the sported fever group. Participants should also be familiar with the pathophysiology of the rickettsial diseases.
立克次体病是一类具有皮肤表现的重要感染性病原体。在流行地区，这些疾病需要重点关注，但在某些可疑病例中，可能的生物恐怖主义行为应促使及时通知相关部门。
在这篇分两部分的综述文章中，我们通过研究有关立克次体病的病理生理学、流行病学、临床表现和治疗的既有及最新信息，对这些多样的疾病进行综述。
利用PubMed搜索相关文章，我们浏览了500多篇文章以撰写一篇基于临床的综述文章。
第一部分聚焦于立克次体病的病理生理学以及斑点热群的临床方面。
在本学习活动的第一部分结束时，参与者应能够讨论斑点热群的所有临床表现和治疗方法。参与者还应熟悉立克次体病的病理生理学。
