Wright Rick W, Boyce Robert H, Michener Todd, Shyr Yu, McCarty Eric C, Spindler Kurt P
Department of Orthopaedic Surgery, Washington University School of Medicine at Barnes-Jewish Hospital, St. Louis, MO 63110, USA.
Clin Orthop Relat Res. 2006 Jan;442:245-51. doi: 10.1097/01.blo.0000167670.03197.c2.
Preoperatively predicting chondral damage is important. Weightbearing radiographs, including the standing anteroposterior and 45 degrees flexion posteroanterior views traditionally have been used for this purpose. We wanted to determine if one radiograph had superior sensitivity or specificity in detecting arthroscopically confirmed Grade II chondromalacia (mild arthritis). A standard prospective standing radiographic protocol was designed for all patients who presented to a sports medicine center with knee complaints. Patients who had subsequent arthroscopic surgery had their radiographs measured in a blinded manner for articular cartilage intervals in millimeters to detect joint-space narrowing. Intraarticular chondral damage was correlated with the radiographic findings. Three hundred forty-nine of a possible 411 (87%) patients during a 2-year period had both radiographs and subsequent arthroscopic grading of chondromalacia. This has been the largest study that correlated arthroscopic chondromalacia grades with two commonly preferred weightbearing radiograph projections. Despite specificities greater than 90%, the sensitivity was extremely low and neither standing radiograph was superior. Neither radiograph was useful in detecting Grade II chondral damage.
Diagnostic study, Level I-1 (testing of previously developed diagnostic criteria in series of consecutive patients--with universally applied reference "gold" standard). See the Guidelines for Authors for a complete description of levels of evidence.
术前预测软骨损伤很重要。传统上,负重X线片,包括站立位前后位和45度屈曲位后前位片,一直用于此目的。我们想确定在检测关节镜证实的II级软骨软化(轻度关节炎)时,一张X线片是否具有更高的敏感性或特异性。为所有因膝关节问题就诊于运动医学中心的患者设计了一种标准的前瞻性站立位X线检查方案。接受后续关节镜手术的患者,其X线片以盲法测量关节软骨间隙(单位为毫米),以检测关节间隙变窄。关节内软骨损伤与X线检查结果相关。在两年期间,411例可能的患者中有349例(87%)既进行了X线检查,又进行了后续关节镜下软骨软化分级。这是将关节镜下软骨软化分级与两种常用的负重X线片投影相关联的最大规模研究。尽管特异性大于90%,但敏感性极低,且两种站立位X线片均无优势。两种X线片在检测II级软骨损伤方面均无用处。
诊断性研究,I-1级(在一系列连续患者中对先前制定的诊断标准进行测试——采用普遍适用的参考“金”标准)。有关证据水平的完整描述,请参阅作者指南。