Kuikka Paavo-Ilari, Kiuru Martti J, Niva Maria H, Kröger Heikki, Pihlajamäki Harri K
Research Institute of Military Medicine, Central Military Hospital, Helsinki, Finland.
Arthroscopy. 2006 Oct;22(10):1033-9. doi: 10.1016/j.arthro.2006.06.021.
The purpose of this study was to evaluate the sensitivity, specificity, and accuracy of routine 1.0-Tesla magnetic resonance imaging (MRI) versus arthroscopy in detecting fresh traumatic chondral lesions of the knee.
Over a period of 6 years, 578 consecutive military personnel underwent MRI before arthroscopy of the knee. Of these, 32 patients with arthroscopically proven fresh traumatic chondral lesions of the knee were chosen for further analysis. A supplementary condition was that arthroscopy was performed no later than 6 weeks after the onset of trauma. The original MRIs and hospital records were re-evaluated and the chondral lesions were graded and compared with arthroscopic findings. The arthroscopic results served as the gold standard when the sensitivity, specificity, and accuracy of MRI were calculated.
The age of the patients ranged from 19 to 21 years (mean, 19.6 years). MRI detected cartilage defects with a sensitivity of 36% (95% confidence interval [CI], 23% to 50%), specificity of 91% (95% CI, 85% to 95%), and diagnostic accuracy of 78% (95% CI, 72% to 83%). MRI results were affected by the grade of the chondral lesions.
This study shows that routine 1.0-T MRI is not sensitive but is specific and somewhat accurate in detecting fresh traumatic articular cartilage lesions. The hypothesis of this study was that 1.0-T MRI could replace diagnostic arthroscopy in the diagnosis of fresh traumatic chondral lesions. Our results fail to support this hypothesis because of the poor sensitivity obtained with MRI.
Level II, development of diagnostic criteria.
本研究旨在评估常规1.0特斯拉磁共振成像(MRI)与关节镜检查在检测膝关节新鲜创伤性软骨损伤方面的敏感性、特异性和准确性。
在6年的时间里,578名连续的军事人员在膝关节镜检查前接受了MRI检查。其中,32例经关节镜证实为膝关节新鲜创伤性软骨损伤的患者被选作进一步分析。一个补充条件是关节镜检查在创伤发生后不迟于6周进行。对原始MRI和医院记录进行重新评估,对软骨损伤进行分级,并与关节镜检查结果进行比较。在计算MRI的敏感性、特异性和准确性时,关节镜检查结果作为金标准。
患者年龄在19至21岁之间(平均19.6岁)。MRI检测软骨缺损的敏感性为36%(95%置信区间[CI],23%至50%),特异性为91%(95%CI,85%至95%),诊断准确性为78%(95%CI,72%至83%)。MRI结果受软骨损伤分级的影响。
本研究表明,常规1.0-T MRI在检测新鲜创伤性关节软骨损伤方面不敏感,但具有特异性且在一定程度上准确。本研究的假设是1.0-T MRI可在新鲜创伤性软骨损伤的诊断中取代诊断性关节镜检查。由于MRI获得的敏感性较差,我们的结果未能支持这一假设。
II级,诊断标准的制定。