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[酒精中毒所致肝损伤中细胞质晶体的电子显微镜研究]

[Electron microscopic study of cytoplasmic crystals in liver damages caused by alcoholism].

作者信息

Schaff Z, Lapis K

出版信息

Morphol Igazsagugyi Orv Sz. 1975 Jan;15(1):30-6.

PMID:163958
Abstract

Liver biopsy of 50 patients with liver disease of alcoholic etiology was examined electronmicroscopically. In every stage of the disease presence of intramitochondrial paracrystalloids was revealed. Hyalin of alcoholic origin of fibrillar structure was seen in cases of alcoholic hepatitis. By the electronmicroscopic examination of three cases of alcoholic fatty liver a special form of cytoplasmatic paracristalloid inclusion could be seen. This inclusion consists of membranless parallely lying fibrills. Changing the plain of the preparats containing inclusions by the aid of a goniometer the structure of the inclusions appeared in a form of "honey-comb". Inclusion in the question can not be regarded identical neither with intramitochondrial inclusions nor with the fibrills of the so called alcoholic hyalin. Formation and function of these inclusions are as yet unknown.

摘要

对50例酒精性病因肝病患者的肝脏活检进行了电子显微镜检查。在疾病的各个阶段均发现线粒体内存在类晶体。在酒精性肝炎病例中可见到具有纤维状结构的酒精源性透明蛋白。通过对3例酒精性脂肪肝的电子显微镜检查,可观察到一种特殊形式的细胞质类晶体包涵体。这种包涵体由无膜平行排列的纤维组成。借助测角仪改变含有包涵体的标本平面时,包涵体的结构呈现出“蜂窝”状。所讨论的这种包涵体既不能被视为与线粒体内包涵体相同,也不能被视为与所谓酒精性透明蛋白的纤维相同。这些包涵体的形成和功能尚不清楚。

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1
[Electron microscopic study of cytoplasmic crystals in liver damages caused by alcoholism].[酒精中毒所致肝损伤中细胞质晶体的电子显微镜研究]
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