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[乳腺癌细胞中核仁形成染色体区域表现的定性和结构特点]

[Qualitative and structural peculiarities of manifestation of nucleoli-forming chromosome regions in breast cancer cells].

作者信息

Tuganova T N, Bolgova L S, Alekseenko O I, Makhortova M H

出版信息

Tsitol Genet. 2005 Jul-Aug;39(4):57-63.

PMID:16396333
Abstract

Qualitative differentiated study and calculation of 44404 main morphofunctional types of nucleoli has been perfomed on Ag-positive punction specimens from 50 patients with glandular breast cancer. Accordance of different for their activity morhofunctional types of nucleoli and extranucleolar argentofil granules to proliferative activity rates, malignant transformation and dystrophic changes of tumor cells has been demonstrated.

摘要

对50例乳腺腺癌患者的银染色阳性穿刺标本进行了44404种主要核仁形态功能类型的定性鉴别研究和计算。已证明核仁及核仁外嗜银颗粒的不同形态功能类型与肿瘤细胞的增殖活性、恶性转化和营养不良性变化之间的相关性。

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