Moghaddam Jamal Akhavan, Amini Mohsen, Adibnejad Soheil
Department of General Surgery, Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Mollasadra Street, Tehran, Iran.
BMC Gastroenterol. 2006 Jan 5;6:1. doi: 10.1186/1471-230X-6-1.
The formation of bile duct bezoars is a rare event. Its occurrence when there is no history of choledochoenteric anastomosis or duodenal diverticulum constitutes an extremely scarce finding.
We present a case of obstructive jaundice, caused by the concretion of enteric material (bezoars) in the common bile duct following choledochoduodenal fistula development. Six years after cholecystectomy, a 60-year-old female presented with abdominal pain and jaundice. Endoscopic retrograde cholangiopancreatography demonstrated multiple filling defects in her biliary tract. The size of the obstructing objects necessitated surgical retrieval of the stones. A histological assessment of the objects revealed fibrinoid materials with some cellular debris. Post-operative T-tube cholangiography (9 days after the operation) illustrated an open bile duct without any filling defects. Surprisingly, a relatively long choledochoduodenal fistula was detected. The fistula formation was assumed to have led to the development of the bile duct bezoar.
Bezoar formation within the bile duct should be taken into consideration as a differential diagnosis, which can alter treatment modalities from surgery to less invasive methods such as more intra-ERCP efforts. Suspicions of the presence of bezoars are strengthened by the detection of a biliary enteric fistula through endoscopic retrograde cholangiopancreatography. Furthermore, patients at a higher risk of fistula formation should undergo a thorough ERCP in case there is a biliodigestive fistula having developed spontaneously.
胆管粪石形成是一种罕见事件。在没有胆总管肠道吻合术或十二指肠憩室病史的情况下发生这种情况是极为罕见的发现。
我们报告一例因胆总管十二指肠瘘形成后,肠道物质(粪石)在胆总管内凝结导致的梗阻性黄疸病例。胆囊切除术后六年,一名60岁女性出现腹痛和黄疸。内镜逆行胰胆管造影显示其胆道有多个充盈缺损。梗阻物体的大小需要通过手术取出结石。对这些物体的组织学评估显示为纤维蛋白样物质及一些细胞碎片。术后T管胆管造影(术后9天)显示胆管通畅,无任何充盈缺损。令人惊讶的是,发现了一个相对较长的胆总管十二指肠瘘。推测瘘的形成导致了胆管粪石的发展。
胆管内粪石形成应作为鉴别诊断予以考虑,这可能会使治疗方式从手术转变为侵入性较小的方法,如更多的内镜逆行胰胆管造影操作。通过内镜逆行胰胆管造影检测到胆肠瘘会增加对粪石存在的怀疑。此外,瘘形成风险较高的患者如果自发形成了胆胰瘘,应接受全面的内镜逆行胰胆管造影检查。