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免疫抑制疗法成功治疗白塞病复发性心内血栓。

Successful treatment of recurrent intracardiac thrombus in Behçet's disease with immunosuppressive therapy.

作者信息

Kaneko Y, Tanaka K, Yoshizawa A, Yasuoka H, Suwa A, Satoh T, Iwanaga S, Ogawa S, Ikeda Y, Hirakata M

机构信息

Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

出版信息

Clin Exp Rheumatol. 2005 Nov-Dec;23(6):885-7.

Abstract

Behçet's disease (BD) is a chronic multisystem inflammatory disorder characterized by recurrent oral and genital ulcers, skin eruptions and uveitis. Neurological, gastrointestinal, and musculoskeletal systems are also involved. Although venous and arterial vasculitis occur in up to one-third of patients, intracardiac thrombus is a very rare complication. We herein report the case of a 46-year-old man with BD who presented with a large right atrial thrombus. Within a month after surgical removal, the thrombus recurred and was successfully treated with immunosuppressants that included prednisolone and cyclophosphamide.

摘要

白塞病(BD)是一种慢性多系统炎症性疾病,其特征为复发性口腔和生殖器溃疡、皮肤疹和葡萄膜炎。神经、胃肠和肌肉骨骼系统也会受累。尽管多达三分之一的患者会发生静脉和动脉血管炎,但心内血栓是一种非常罕见的并发症。我们在此报告一例46岁患有白塞病的男性患者,该患者出现了一个巨大的右心房血栓。手术切除后的一个月内,血栓复发,随后使用包括泼尼松龙和环磷酰胺在内的免疫抑制剂成功治疗。

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