血管免疫母细胞性T细胞淋巴瘤：干燥综合征中一种相对常见的T细胞淋巴瘤类型。
Angioimmunoblastic T-cell lymphoma: a relatively common type of T-cell lymphoma in Sjögren's syndrome.
作者信息
Saito M, Fukuda T, Shiohara T, Homori M
机构信息
Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160-8582, Japan.
出版信息
Clin Exp Rheumatol. 2005 Nov-Dec;23(6):888-90.
An increased risk of developing lymphoma has been indicated in Sjögren's syndrome (SS), and the lymphomas in SS are usually B-cell type in origin. Interestingly, despite the rather low frequency of T-cell lymphoma in SS, angioimmunoblastic T-cell lymphoma (AILD) constitute the majority of T-cell lymphomas associated with SS. To the best of our knowledge, including our case, at least 11 out of 23 (48%) cases of T-cell lymphoma reported in association with SS, were AILD. The fact that the development of B-cell lymphoma in SS is much more frequent than that of T-cell lymphoma, might be explained by differences in the situation between B and T cells, although the exact mechanism still remains uncertain.
干燥综合征（SS）患者发生淋巴瘤的风险增加，且SS中的淋巴瘤通常起源于B细胞类型。有趣的是，尽管SS中T细胞淋巴瘤的发生率相当低，但血管免疫母细胞性T细胞淋巴瘤（AILD）构成了与SS相关的T细胞淋巴瘤的大多数。据我们所知，包括我们的病例在内，在报告的与SS相关的23例T细胞淋巴瘤病例中，至少有11例（48%）是AILD。SS中B细胞淋巴瘤的发生比T细胞淋巴瘤更为频繁，这一事实可能是由B细胞和T细胞的情况差异所解释的，尽管确切机制仍不确定。
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