Sinks G D, Quigley J D, Reinemeyer C R
Department of Animal Science, University of Tennessee, Knoxville 37901.
J Am Vet Med Assoc. 1992 Jun 15;200(12):1947-51.
Effects of lasalocid on coccidial infection and on calf growth were examined in 16 Holstein bull calves. Calves were assigned randomly to a 2 x 2 factorial arrangement of starter ration containing 0 or 40 mg of lasalocid/kg of starter, beginning when calves were 3 days old (SE = 0.046), and single oral inoculation with 0 or 30,000 sporulated oocysts (Eimeria bovis) at 28 days. Pelleted calf starter was fed ad libitum from day 1; milk replacer was fed at a rate of 3.6 kg/d until day 28. Mean daily gain, dry-matter intake, and body weight were increased in calves fed lasalocid and decreased in those inoculated with coccidia. Addition of lasalocid to the feed improved gains by 8% in uninoculated calves and by 50% in inoculated calves. Fecal oocyst numbers were reduced when lasalocid was fed to inoculated calves. Feces were more abnormal in calves inoculated with coccidia. Respiration rates, rectal temperatures, PCV, and serum sodium and potassium concentrations were unaffected by treatment. On the basis of findings in this study, lasalocid minimized effects of coccidial challenge inoculation and increased growth of calves.
在16头荷斯坦公牛犊中研究了拉沙洛西对球虫感染及犊牛生长的影响。犊牛从3日龄（标准误=0.046）开始被随机分配到含有0或40毫克拉沙洛西/千克开食料的2×2析因设计开食料组，并在28日龄时单次口服接种0或30,000个孢子化卵囊（牛艾美耳球虫）。从第1天开始随意饲喂颗粒状犊牛开食料；代乳料以3.6千克/天的速率饲喂至28日龄。饲喂拉沙洛西的犊牛平均日增重、干物质摄入量和体重增加，而接种球虫的犊牛则降低。在未接种的犊牛中，在饲料中添加拉沙洛西使增重提高了8%，在接种的犊牛中提高了50%。给接种球虫的犊牛饲喂拉沙洛西时，粪便中卵囊数量减少。接种球虫的犊牛粪便更不正常。呼吸频率、直肠温度、红细胞压积以及血清钠和钾浓度不受处理影响。根据本研究的结果，拉沙洛西可将球虫攻击接种的影响降至最低，并增加犊牛的生长。
