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The magnetic resonance imaging contrast agent mangafodipir exerts antitumor activity via a previously described superoxide dismutase mimetic activity.

作者信息

Karlsson Jan Olof G, Brurok Heidi, Towart Rob, Jynge Per

出版信息

Cancer Res. 2006 Jan 1;66(1):598; author reply 598. doi: 10.1158/0008-5472.CAN-05-2053.

DOI:10.1158/0008-5472.CAN-05-2053
PMID:16397277
Abstract
摘要

相似文献

1
The magnetic resonance imaging contrast agent mangafodipir exerts antitumor activity via a previously described superoxide dismutase mimetic activity.
Cancer Res. 2006 Jan 1;66(1):598; author reply 598. doi: 10.1158/0008-5472.CAN-05-2053.
2
Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir.超氧化物歧化酶模拟物锰福地吡改善抗癌药物的治疗指数
J Natl Cancer Inst. 2006 Feb 15;98(4):236-44. doi: 10.1093/jnci/djj049.
3
Protective effects of mangafodipir against chemotherapy-induced ovarian damage in mice.镁替普酶对化疗诱导的小鼠卵巢损伤的保护作用。
Reprod Biol Endocrinol. 2018 Oct 27;16(1):106. doi: 10.1186/s12958-018-0426-y.
4
Contrast-enhanced magnetic resonance cholangiography using mangafodipir compared with standard T2W MRC sequences: a pictorial essay.
J Magn Reson Imaging. 2004 Aug;20(2):256-63. doi: 10.1002/jmri.20114.
5
Antioxidant activity of mangafodipir is not a new finding.锰福地吡的抗氧化活性并非新发现。
J Hepatol. 2004 May;40(5):872-3; author reply 873. doi: 10.1016/j.jhep.2004.02.022.
6
Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties.卡锰福地吡[Ca4Mn(DPDP)5]、锰福地吡(MnDPDP)和锰基发光二极管，特别提及它们的超氧化物歧化酶模拟物和治疗特性。
Drug Discov Today. 2015 Apr;20(4):411-21. doi: 10.1016/j.drudis.2014.11.008. Epub 2014 Nov 20.
7
[MnDPDP--contrast medium with protective effect in acute myocardial infarction].[锰双吡啶二磷酸盐——急性心肌梗死中有保护作用的造影剂]
Lakartidningen. 2002 Oct 3;99(40):3955-6.
8
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity.化疗诱导的肿瘤细胞杀伤和正常组织毒性的氧化还原调节。
J Natl Cancer Inst. 2006 Feb 15;98(4):223-5. doi: 10.1093/jnci/djj065.
9
Metal ion chelating peptides with superoxide dismutase activity.具有超氧化物歧化酶活性的金属离子螯合肽。
Biomed Pharmacother. 2005 May;59(4):158-62. doi: 10.1016/j.biopha.2005.03.008. Epub 2005 Mar 19.
10
Re: diagnostic accuracy of portal-phase CT and MRI with mangafodipir trisodium in detecting liver metastases from colorectal carcinoma.回复：门静脉期CT及使用锰福地匹三钠的MRI在检测结直肠癌肝转移方面的诊断准确性
Clin Radiol. 2007 Aug;62(8):817; author reply 817. doi: 10.1016/j.crad.2007.01.028. Epub 2007 May 22.

引用本文的文献

1
Superior therapeutic index of calmangafodipir in comparison to mangafodipir as a chemotherapy adjunct.与螯合型钆弗塞胺相比，钆塞酸二钠作为化疗辅助药物具有更高的治疗指数。
Transl Oncol. 2012 Dec;5(6):492-502. doi: 10.1593/tlo.12238. Epub 2012 Dec 1.
2
Effects of MnDPDP and ICRF-187 on Doxorubicin-Induced Cardiotoxicity and Anticancer Activity.MnDPDP 和 ICRF-187 对多柔比星致心肌毒性和抗癌活性的影响。
Transl Oncol. 2012 Aug;5(4):252-9. doi: 10.1593/tlo.11304. Epub 2012 Aug 1.
3
First clinical experience with the magnetic resonance imaging contrast agent and superoxide dismutase mimetic mangafodipir as an adjunct in cancer chemotherapy-a translational study.
首例磁共振成像对比剂和超氧化物歧化酶模拟物锰铁叶红素作为癌症化疗辅助剂的临床应用——一项转化研究。
Transl Oncol. 2012 Feb;5(1):32-8. doi: 10.1593/tlo.11277. Epub 2012 Feb 1.