眯着眼看斑马鱼的轴。
Squinting at the zebrafish axis.
作者信息
Kimelman David
机构信息
Department of Biochemistry, Box 357350, University of Washington, Seattle, Washington 98195, USA.
出版信息
Dev Cell. 2006 Jan;10(1):6-7. doi: 10.1016/j.devcel.2005.11.001.
PMID:16399072
Abstract
The Nodal family of signaling molecules includes critical intercellular regulators of early vertebrate development. In a recent issue of Nature, maternal transcripts encoding the zebrafish nodal squint were shown to be localized to the future organizer region by the four-cell stage, providing the earliest evidence of embryonic axis asymmetry in the zebrafish embryo.
摘要
信号分子的Nodal家族包括早期脊椎动物发育的关键细胞间调节因子。在最近一期的《自然》杂志上，编码斑马鱼Nodal斜视蛋白的母源转录本在四细胞期被定位到未来的组织者区域，这为斑马鱼胚胎中的胚胎轴不对称提供了最早的证据。
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