心力衰竭患者的低钠血症
Hyponatremia in patients with heart failure.
作者信息
De Luca Leonardo, Klein Liviu, Udelson James E, Orlandi Cesare, Sardella Gennaro, Fedele Francesco, Gheorghiade Mihai
机构信息
Department of Cardiovascular and Respiratory Sciences, La Sapienza University, Rome, Italy.
出版信息
Am J Cardiol. 2005 Dec 19;96(12A):19L-23L. doi: 10.1016/j.amjcard.2005.09.066. Epub 2005 Oct 5.
Mild hyponatremia is encountered frequently in patients hospitalized for worsening heart failure. Admission plasma sodium concentration appears to be an independent predictor of increased mortality after discharge and rehospitalization. Recent studies have suggested that correction of hyponatremia may be associated with improved survival. This hypothesis is currently being studied in large prospective randomized clinical trials.
轻度低钠血症在因心力衰竭加重而住院的患者中很常见。入院时的血浆钠浓度似乎是出院后和再次住院后死亡率增加的独立预测因素。最近的研究表明，纠正低钠血症可能与生存率提高有关。目前正在大型前瞻性随机临床试验中对这一假设进行研究。
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