Rosen Evan D
Division of Endocrinology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA.
Cell Metab. 2006 Jan;3(1):1-2. doi: 10.1016/j.cmet.2005.12.002.
Signal transduction cascades, such as Hedgehog (Hh) signaling, are potentially important targets for new drugs. A new study in this issue of Cell Metabolism identifies hedgehog signaling in the formation of the Drosophila fly body and in mammalian adipogenesis.
信号转导级联反应,如刺猬信号通路(Hh信号通路),可能是新药的重要潜在靶点。本期《细胞代谢》中的一项新研究确定了刺猬信号通路在果蝇身体形成和哺乳动物脂肪生成中的作用。