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传统体外循环冠状动脉旁路移植手术中吻合口的质量:使用U形夹的间断技术的影响及其与术中移植血管血流模式的相关性。

Quality of anastomosis in conventional on-pump coronary artery bypass graft surgery: influence of the interrupted technique using u-clips and correlation with intraoperative graft flow patterns.

作者信息

Mayuga Kenneth A, Harper Baron

机构信息

University of Illinois College of Medicine-Rockford, Rockford, Illinois, USA.

出版信息

Heart Surg Forum. 2006;9(1):E518-21. doi: 10.1532/HSF98.20051157.

Abstract

BACKGROUND

The interrupted suture technique in creating graft-coronary artery anastomoses in coronary artery bypass graft (CABG) surgery is hypothesized to be superior to the standard continuous technique. However, because of the increased time and knot tying involved with the interrupted technique, the continuous suture became standard. In 2000, the U-clip (a self-closing metal clip) was introduced to help in creating an interrupted anastomosis, although data regarding its clinical use are still somewhat limited. Intraop-erative transit-time flow measurement (TTFM) of blood flow through an anastomosis is frequently used to assess quality of anastomosis creation; mean flow and pulsatile index (PI) are analyzed. PI should typically be between 1 and 5; higher values are associated with errors of anastomosis creation. The current study analyzes the difference in TTFM between U-clips and standard suture in CABG surgery.

METHODS

The study population consists of 30 prospectively enrolled patients undergoing first-time on-pump conventional CABG surgery at St. Anthony Medical Center who were randomized to have their anastomosis created with either U-clips or suture. TTFM were recorded for left internal mammary artery to left anterior descending artery (LIMA-LAD) anastomoses.

RESULTS

Of the 30 subjects enrolled (10 women), 12 operations were done with U-clips and 18 with suture. Body mass index (BMI) in the 2 groups was similar. In terms of mean flow, there was no difference between the 2 groups (29.8 +/- 18.4 mL/min for U-clips versus 26.6 +/- 11.0 mL/min for suture, P = .57). In terms of PI, again no difference was found (3.1 +/- 1.3 for U-clips versus 2.5 +/- 0.8 for suture, P = .12).

CONCLUSIONS

The findings of this study suggest that U-clips are comparable to the standard suture for LIMA-LAD anastomoses in conventional on-pump CABG surgery in terms of intraoperative assessment of graft flow.

摘要

背景

在冠状动脉旁路移植术(CABG)中,用于创建移植血管与冠状动脉吻合口的间断缝合技术被认为优于标准的连续缝合技术。然而,由于间断缝合技术所需时间增加且打结操作更多,连续缝合成为了标准方法。2000年,U形夹(一种自动闭合的金属夹)被引入以辅助创建间断吻合口,尽管关于其临床应用的数据仍较为有限。术中通过吻合口的血流的渡越时间血流测量(TTFM)常用于评估吻合口创建的质量;分析平均血流和搏动指数(PI)。PI通常应在1至5之间;较高的值与吻合口创建错误相关。本研究分析了CABG手术中U形夹与标准缝合在TTFM方面的差异。

方法

研究人群包括30例在圣安东尼医疗中心接受首次体外循环常规CABG手术的前瞻性入组患者,他们被随机分配使用U形夹或缝合线进行吻合口创建。记录左乳内动脉至左前降支动脉(LIMA-LAD)吻合口的TTFM。

结果

在入组的30名受试者(10名女性)中,12例手术使用U形夹,18例使用缝合线。两组的体重指数(BMI)相似。在平均血流方面,两组之间无差异(U形夹组为29.8±18.4 mL/分钟,缝合线组为26.6±11.0 mL/分钟,P = 0.57)。在PI方面,同样未发现差异(U形夹组为3.1±1.3,缝合线组为2.5±0.8,P = 0.12)。

结论

本研究结果表明,在常规体外循环CABG手术中,就术中对移植血管血流的评估而言,U形夹与用于LIMA-LAD吻合口的标准缝合相当。

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