Hassanein Wael, Albert Alexander A, Arnrich Bert, Walter Joerg, Ennker Ina Carolin, Rosendahl Ulrich, Bauer Stefan, Ennker Juergen
Clinic for Cardiothoracic Surgery, Heart Institute Lahr/Baden, Lahr, Germany.
Ann Thorac Surg. 2005 Dec;80(6):2155-61. doi: 10.1016/j.athoracsur.2005.03.138.
Off-pump coronary artery bypass grafting (OPCAB) has attracted increasing attention. Performing the anastomosis off-pump is technically more demanding. The objective of the study is to assess the quality of anastomosis in OPCAB in comparison with conventional on-pump coronary artery bypass grafting using the transit time flow measurement.
Four hundred forty-five patients operated on using OPCAB technique were included in the study. For each patient in this group a similar patient from the on-pump coronary artery bypass grafting population was selected according to the number of grafts, bypass material, and target coronary arteries. The mean flow and the pulsatile index were measured in every bypass graft in both groups.
The average pulsatile index in OPCAB was 2.09 +/- 1.03 (mean flow, 39 +/- 22.63 mL/min), whereas with on-pump coronary artery bypass grafting it was 1.9 +/- 0.98 (mean flow, 44.19 +/- 23.58 mL/min); p = 0.005. Subgroup analysis showed significantly lower mean flows and higher pulsatile index with OPCAB in grafts to the obtuse marginal, diagonal, and right coronary artery, but not to the left anterior descending territory.
The quality of the anastomosis performed using the OPCAB technique might be jeopardized by less accessibility as in the case of lateral and posterior wall coronary arteries. Techniques to optimize the accessibility of the coronary artery like combining sling support with cup stabilizers, together with systematic training, should be strongly considered in OPCAB. Whenever there is good accessibility of the coronary artery as in the case of the left anterior descending, the anastomosis performed under OPCAB has a quality as good as that performed using the conventional technique.
非体外循环冠状动脉旁路移植术(OPCAB)已引起越来越多的关注。非体外循环下进行吻合技术要求更高。本研究的目的是通过使用渡越时间血流测量法,比较OPCAB与传统体外循环冠状动脉旁路移植术中吻合口的质量。
本研究纳入了445例行OPCAB技术手术的患者。根据移植血管数量、旁路材料和目标冠状动脉,为该组中的每位患者从体外循环冠状动脉旁路移植术人群中选择一名相似患者。测量两组中每个旁路移植血管的平均血流和搏动指数。
OPCAB组的平均搏动指数为2.09±1.03(平均血流,39±22.63 mL/min),而体外循环冠状动脉旁路移植术组为1.9±0.98(平均血流,44.19±23.58 mL/min);p = 0.005。亚组分析显示,在钝缘支、对角支和右冠状动脉的移植血管中,OPCAB的平均血流显著降低,搏动指数更高,但在左前降支区域并非如此。
对于侧壁和后壁冠状动脉,由于可及性较差,采用OPCAB技术进行吻合的质量可能会受到影响。在OPCAB中,应强烈考虑采用如将吊带支撑与杯状稳定器相结合等优化冠状动脉可及性的技术,同时进行系统培训。当冠状动脉可及性良好时,如左前降支的情况,OPCAB下进行的吻合质量与传统技术相当。