Bell Caroline J, Nicholson Helen, Mulder Roger T, Luty Sue E, Joyce Peter R
Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand.
J Psychopharmacol. 2006 Sep;20(5):656-60. doi: 10.1177/0269881106060512. Epub 2006 Jan 9.
Evidence suggests that the neuropeptide oxytocin plays a role in social affiliation. This behaviour may be related more to personality dimensions than specific psychiatric diagnoses. This study investigated the relationship between plasma oxytocin levels and personality dimensions using the Temperament and Character Inventory (TCI) in 60 outpatients with major depression. The strongest correlation was between plasma oxytocin levels and the temperament dimension of Reward Dependence (0.425 Pearson correlation). This suggested that 17% of the variance in plasma oxytocin levels was explained by the Reward Dependence scores. There was a significant positive correlation between plasma oxytocin levels and the Reward Dependence personality dimension.
有证据表明，神经肽催产素在社会依恋中发挥作用。这种行为可能与人格维度的关系更大，而非特定的精神疾病诊断。本研究使用气质与性格量表（TCI），对60名重度抑郁症门诊患者的血浆催产素水平与人格维度之间的关系进行了调查。血浆催产素水平与奖赏依赖的气质维度之间的相关性最强（皮尔逊相关系数为0.425）。这表明，血浆催产素水平17%的变异可由奖赏依赖得分来解释。血浆催产素水平与奖赏依赖人格维度之间存在显著的正相关。
