Faes Luca, Widesott Lamberto, Del Greco Maurizio, Antolini Renzo, Nollo Giandomenico
Laboratorio Biosegnali, Dipartimento di Fisica, Università di Trento, Italy.
IEEE Trans Biomed Eng. 2006 Jan;53(1):65-73. doi: 10.1109/TBME.2005.859788.
A causal approach to the calculation of coherence and transfer function between systolic pressure (SP) and RR interval variability was applied in eight patients and eight control subjects during prolonged tilt test for investigating the impairment of cardiovascular control related to neurally mediated syncope. The causal analysis showed a depressed baroreflex regulation in resting patients, with reduced gain and increased latency from SP to RR, and a drop of the baroreflex coupling immediately before syncope. These findings, which were not elicited by traditional cross-spectral analysis, strongly suggest the use of the causal approach for the study of syncope mechanisms.
在八名患者和八名对照受试者进行长时间倾斜试验期间，采用因果分析方法计算收缩压（SP）与RR间期变异性之间的相干性和传递函数，以研究与神经介导性晕厥相关的心血管控制损害。因果分析显示，静息患者的压力反射调节功能减退，从SP到RR的增益降低且潜伏期延长，且在晕厥前压力反射耦合立即下降。这些传统互谱分析未得出的结果强烈表明应采用因果分析方法来研究晕厥机制。
