Astrup Arne V, Rössner Stephan, Sørensen Thorkild I A
Den Kongelige Veterinaer og Landbohøjskole, Levnedsmiddelcentret, Institut for Human Ernaering, Huddninge Universitetssjukhus, Overviktsenheten, og Center for Sundhed og Samfund.
Ugeskr Laeger. 2006 Jan 9;168(2):135-7.
The prevailing understanding of the causes of obesity is based on the disturbance of the thermodynamic law of energy balance, primarily through increased intake or decreased expenditure of energy. Alternative causes of obesity, which still respect the law but also allow for primary fat accumulation, are: virus infection of fat cells, energy supply from bacterial fermentation of indigestible food components, psychosocial factors mediated by psychoneuroendocrine pathways, sleeplessness or poor quality of sleep and early life programming, in addition to the well-known and proven genetic programming.
目前对肥胖成因的理解基于能量平衡热力学定律的紊乱，主要是通过能量摄入增加或消耗减少。肥胖的其他成因，虽仍遵循该定律但也存在原发性脂肪堆积的情况，包括：脂肪细胞的病毒感染、难消化食物成分的细菌发酵产生的能量供应、由心理神经内分泌途径介导的社会心理因素、失眠或睡眠质量差以及生命早期编程，此外还有众所周知且已得到证实的基因编程。
