Madsbad Sten, Richelsen Bjørn
H:S Hvidovre Hospital, Endokrinologisk Afdeling, Hvidovre.
Ugeskr Laeger. 2006 Jan 9;168(2):175-9.
Weight loss of several kilograms improves glycaemic control and the lipid profile and reduces blood pressure. A consultation with a clinical dietician who is educated in behaviour therapy can, for many patients, induce a weight loss of 5-10%. The use of orlistat and sibutramine has been shown to increase weight loss by about 2-6 kilograms. A very-low-calorie diet (VLCD) promotes faster and greater weight loss. Surgical treatment of obesity results in considerable weight loss and often normalisation of blood glucose levels. Except for surgically treated patients, most patients begin to regain the weight lost four to six months after the start of the change in diet.
体重减轻几千克可改善血糖控制、血脂水平并降低血压。对于许多患者而言,咨询接受过行为疗法培训的临床营养师可促使体重减轻5% - 10%。已证明使用奥利司他和西布曲明可使体重额外减轻约2 - 6千克。极低热量饮食(VLCD)能促进更快且更大量的体重减轻。肥胖症的手术治疗可导致显著的体重减轻,且常使血糖水平恢复正常。除接受手术治疗的患者外,大多数患者在开始改变饮食四至六个月后会开始重新恢复已减轻的体重。