Heller Marissa
Department of Dermatology, New York University School of Medicine, USA.
Dermatol Online J. 2005 Dec 30;11(4):25.
A 42-year-old man with a 2-year history of left posterior uveitis and recurrent oral aphthous ulcers presented for evaluation of recurrent, erythematous, subcutaneous, tender nodules on his lower extremities. A biopsy specimen of the nodules showed a medium-sized-vessel vasculitis with a mild and moderate inflammatory cell infiltrate in the septae and lobules of the subcutaneous adipose tissue. These changes were consistent with cutaneous polyarteritis nodosa. Behçet disease is a multisystem inflammatory disorder that includes recurrent oral aphthous ulcers, and at least two of the following features: recurrent genital ulcers, eye lesions, skin lesions, and a positive pathergy test. Behçet disease and cutaneous polyarteritis nodosa have rarely been described in conjunction, and the suggestion has been raised that cutaneous polyarteritis-nodosa-like lesions may actually be a cutaneous marker of Behçet disease.
一名42岁男性，有2年的左后葡萄膜炎和复发性口腔阿弗他溃疡病史，因下肢反复出现红斑性、皮下、压痛性结节前来评估。结节的活检标本显示为中等大小血管炎，皮下脂肪组织的间隔和小叶有轻度和中度炎症细胞浸润。这些改变符合皮肤型结节性多动脉炎。白塞病是一种多系统炎症性疾病，包括复发性口腔阿弗他溃疡，以及以下至少两种特征：复发性生殖器溃疡、眼部病变、皮肤病变和针刺反应阳性。白塞病和皮肤型结节性多动脉炎很少同时被描述，有人提出皮肤型结节性多动脉炎样病变实际上可能是白塞病的皮肤标志物。
