Kwong Rhonda A, Kossard Steven
Dermatology Research Laboratories, Central Clinical School, University of Sydney, Sydney, New South Wales, Australia.
Australas J Dermatol. 2006 Feb;47(1):63-6. doi: 10.1111/j.1440-0960.2006.00227.x.
SUMMARY Postmenopausal women with frontal recession may represent a diagnostic challenge, as frontal fibrosing alopecia and alopecia areata may be clinically difficult to distinguish. A 53-year-old postmenopausal woman presented with a progressive fronto-temporal marginal alopecia with sparing of her eyebrows. Scalp biopsy of the affected frontal hairline revealed peribulbar lymphocytic inflammation, but no evidence of lichenoid inflammation, perifollicular fibrosis or scarring. Whereas the pathology strongly favoured alopecia areata, the clinical features overlapped with frontal fibrosing alopecia, a variant of lichen planopilaris targeting the frontal scalp. This paper presents an atypical clinical presentation of alopecia areata, which may be mistaken for frontal fibrosing alopecia.
摘要 绝经后出现额部头发后退的女性可能是一个诊断难题,因为临床上很难区分额部纤维性脱发和斑秃。一名53岁的绝经后女性出现进行性额颞部边缘性脱发,眉毛未受累。对受影响的额部发际线进行头皮活检,显示毛囊周围淋巴细胞炎症,但无苔藓样炎症、毛囊周纤维化或瘢痕形成的证据。虽然病理结果强烈支持斑秃,但临床特征与额部纤维性脱发重叠,额部纤维性脱发是扁平苔藓累及头皮的一种变异型,主要累及额部头皮。本文介绍了斑秃的一种非典型临床表现,其可能被误诊为额部纤维性脱发。