Claude Valère, Blanchet Philippe, Grossin Maggy, Hénin Dominique
Service d'Anatomie et de Cytologie Pathologique, 74575 Paris, France.
Ann Pathol. 2002 Sep;22(4):328-30.
Postmenopausal frontal fibrosing alopecia is a rare aspect of scarring alopecia concerning elderly women. It appears as a receding anterior hair line localised in the frontal and temporal regions. It is a particular pathologic and clinical form of lichen planopilaris. The histologic aspect is that of a lichenoïd inflammatory infiltrate affecting the dermal follicular junction, accompanied by a fibrous scarring aspect, the latter contributing to the diagnosis and individualization of this entity. Discoïd lupus erythematous is the main histologic differential diagnosis. Postmenopausal period is the only associated condition found in affected women. Evolution is unpredictable and does not seem to be modified by treatment.
绝经后额部纤维性脱发是一种发生于老年女性的罕见瘢痕性脱发。表现为额部和颞部发际线后移。它是扁平苔藓样毛发扁平苔藓的一种特殊病理和临床形式。组织学表现为苔藓样炎性浸润累及真皮毛囊交界处,伴有纤维瘢痕形成,后者有助于该疾病的诊断和个体化。盘状红斑狼疮是主要的组织学鉴别诊断。绝经后期是受影响女性中唯一发现的相关情况。病情发展不可预测,治疗似乎无法改变其进程。