Hashim H, Abrams P
Bristol Urological Institute, Southmead Hospital, Westbury-on-Trym, Bristol, United Kingdom.
J Urol. 2006 Jan;175(1):191-4; discussion 194-5. doi: 10.1016/S0022-5347(05)00067-4.
We determined how well the symptoms of OAB syndrome correlate with urodynamic DO using International Continence Society definitions.
The study included adult males and females 18 years or older who attended a tertiary referral center for urodynamics from February 2002 to February 2004. Patients were selected based on OAB syndrome symptoms (urgency, urgency urinary incontinence and frequency). The percent of patients who had symptoms alone or in combination and DO was calculated.
There was a better correlation in results between OAB symptoms and the urodynamic diagnosis of DO in men than in women. Of men 69% and 44% of women with urgency (OAB dry) had DO, while 90% of men and 58% of women with urgency and urgency urinary incontinence (OAB wet) had DO. Stress urinary incontinence seems to have accounted for the decreased rates in women since 87% of women with urgency urinary incontinence also had the symptom of stress urinary incontinence. The ICS definition does not specify what constitutes abnormal voiding frequency. Analysis of results showed that increasing voiding frequency did not have any effect on increasing the accuracy of diagnosis of DO except in women with 10 or more daytime micturition episodes.
The bladder is a better and more reliable witness in men than in women with a greater correlation between OAB symptoms and urodynamic DO, more so in the OAB wet than in OAB dry patients.
我们使用国际尿控协会的定义,确定膀胱过度活动症(OAB)综合征的症状与尿动力学逼尿肌过度活动(DO)之间的关联程度。
该研究纳入了2002年2月至2004年2月期间在一家三级转诊中心接受尿动力学检查的18岁及以上成年男性和女性。根据OAB综合征症状(尿急、急迫性尿失禁和尿频)选择患者。计算单独出现症状或症状组合以及存在DO的患者百分比。
男性中OAB症状与尿动力学DO诊断结果之间的相关性比女性更好。尿急(OAB干型)的男性患者中有69%存在DO,女性患者中有44%存在DO;而尿急合并急迫性尿失禁(OAB湿型)的男性患者中有90%存在DO,女性患者中有58%存在DO。压力性尿失禁似乎是导致女性比例下降的原因,因为87%的急迫性尿失禁女性患者也有压力性尿失禁症状。国际尿控协会的定义未明确规定何为异常排尿频率。结果分析表明,除了白天排尿次数达10次或更多的女性外,排尿频率增加对提高DO诊断准确性没有任何影响。
在OAB症状与尿动力学DO之间的相关性方面,膀胱在男性中比在女性中是更好且更可靠的指征,在OAB湿型患者中比在OAB干型患者中更是如此。