Digesu G Alessandro, Khullar Vik, Cardozo Linda, Salvatore Stefano
Department of Urogynaecology, King's College Hospital, London, United Kingdom.
Neurourol Urodyn. 2003;22(2):105-8. doi: 10.1002/nau.10099.
The aim of our study was to determine whether the urodynamic diagnosis is useful in the management of women with symptoms of an overactive bladder (OAB).
Women with lower urinary tract symptoms, attending a tertiary referral urogynaecology clinic were studied. All women were fully evaluated, with history, urinary symptoms questionnaire, frequency-volume chart, vaginal examination, and videocystourethrography. Women with symptoms consistent with an overactive bladder (urinary frequency, urgency, and/or urge incontinence) were selected. Women with neurological disorders were excluded. Finally, urinary symptoms and urodynamic diagnosis were correlated. All terms and definitions are in accordance with the International Continence Society [Abrams et al., 1988, Scand J Urol Nephrol 114(Suppl):5-19.].
A total of 4,500 women 22-73 years of age were studied. Only 843 women (18.7%) could be classified as having an OAB. Of these, 457 women (54.2%) had urodynamically proven detrusor instability, whereas 386 women (45.8%) had a stable urodynamic trace. Sixty-eight (8.1%) of the women studied had postvoid residual greater than 100 mL. Of the 4,500 women studied, 1,641 (36.5%) had detrusor instability on laboratory urodynamics. Only 27.5% of these women (457 of 1,641) had OAB symptoms.
Symptomatic diagnosis of OAB does not correlate with a urodynamic diagnosis of detrusor instability. The diagnosis of overactive bladder based on urinary symptoms underdiagnoses the condition of detrusor instability in a population of women suffering from lower urinary tract symptoms. Therefore, symptomatic diagnosis of OAB alone is not recommended. Our study suggested that urodynamic evaluation is mandatory in the management of the women with symptoms of an overactive bladder.
我们研究的目的是确定尿动力学诊断对于有膀胱过度活动症(OAB)症状的女性的管理是否有用。
对在三级转诊泌尿妇科诊所就诊的有下尿路症状的女性进行研究。所有女性均接受了全面评估,包括病史、尿路症状问卷、频率 - 尿量图表、阴道检查和膀胱尿道造影。选择有与膀胱过度活动症相符症状(尿频、尿急和/或急迫性尿失禁)的女性。排除患有神经系统疾病的女性。最后,将尿路症状与尿动力学诊断进行关联。所有术语和定义均符合国际尿控协会[艾布拉姆斯等人,1988年,《斯堪的纳维亚泌尿学与肾脏病学杂志》114(增刊):5 - 19]。
共研究了4500名年龄在22至73岁之间的女性。只有843名女性(18.7%)可被归类为患有膀胱过度活动症。其中,457名女性(54.2%)尿动力学证实存在逼尿肌不稳定,而386名女性(45.8%)尿动力学轨迹稳定。所研究的女性中有68名(8.1%)排尿后残余尿量超过100毫升。在4500名研究女性中,1641名(36.5%)在实验室尿动力学检查中有逼尿肌不稳定。这些女性中只有27.5%(1641名中的457名)有膀胱过度活动症症状。
膀胱过度活动症的症状性诊断与逼尿肌不稳定的尿动力学诊断不相关。基于尿路症状对膀胱过度活动症的诊断会低估患有下尿路症状的女性群体中逼尿肌不稳定的情况。因此,不建议仅进行膀胱过度活动症的症状性诊断。我们的研究表明,对于有膀胱过度活动症症状的女性进行管理时,尿动力学评估是必不可少的。