Bogner Hillary R, Ford Daniel E, Gallo Joseph J
Department of Family Practice and Community Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.
Am J Geriatr Psychiatry. 2006 Jan;14(1):71-8. doi: 10.1097/01.JGP.0000192479.82189.e1.
The objective of this study was to describe the influence of cardiovascular disease (CVD) on identification and management of depression by primary care physicians.
Three hundred fifty-five adults with and without significant depressive symptoms who were screened in primary care offices and invited to participate completed a baseline in-home assessment. CVD was assessed by self-report and psychologic status was assessed with commonly used, validated standard questionnaires. At the index visit, doctors' ratings of depression and reports of active management were obtained on 340 of the 355 patients who completed in-home interviews.
Older adults who reported heart failure were more likely to be identified as depressed than were older adults who did not report heart failure (unadjusted odds ratio [OR]: 2.34; 95% confidence interval [CI]: 1.13-4.85; Wald chi(2) = 5.20, df = 1, p = 0.023). In multivariate models that controlled for potentially influential characteristics such as age, marital status, education, ethnicity, functional status, level of depression, cognitive impairment, attitudes about depression, use of medical care, and number of medications, the findings remained statistically significant. Among older adults identified as depressed, older adults with heart failure were significantly less likely to be actively managed for depression than were older adults without heart failure (unadjusted OR: 0.33; 95% CI: 0.14-0.76; Wald chi(2) = 6.73, df = 1, p = 0.009). After controlling for potentially influential covariates, these findings remained substantially unchanged.
CVD, in particular heart failure, may influence the identification and management of depression among older patients by primary care physicians. The findings underlie the importance of developing interventions that integrate the management of depression and CVD in primary care settings.
本研究的目的是描述心血管疾病(CVD)对初级保健医生识别和管理抑郁症的影响。
在初级保健诊所接受筛查并被邀请参与的355名有或无明显抑郁症状的成年人完成了一次基线家庭评估。通过自我报告评估心血管疾病,并用常用的、经过验证的标准问卷评估心理状态。在首次就诊时,从完成家庭访谈的355名患者中的340名患者处获得了医生对抑郁症的评分和积极管理的报告。
报告有心力衰竭的老年人比未报告心力衰竭的老年人更有可能被识别为患有抑郁症(未调整优势比[OR]:2.34;95%置信区间[CI]:1.13 - 4.85;Wald卡方(2)=5.20,自由度=1,p = 0.023)。在控制了年龄、婚姻状况、教育程度、种族、功能状态、抑郁程度、认知障碍、对抑郁症的态度、医疗保健使用情况和药物数量等潜在影响因素的多变量模型中,这些发现仍具有统计学意义。在被识别为患有抑郁症的老年人中,患有心力衰竭的老年人比没有心力衰竭的老年人接受抑郁症积极管理的可能性显著更低(未调整OR:0.33;95%CI:0.14 - 0.76;Wald卡方(2)=6.73,自由度=1,p = 0.009)。在控制了潜在影响协变量后,这些发现基本保持不变。
心血管疾病,尤其是心力衰竭,可能会影响初级保健医生对老年患者抑郁症的识别和管理。这些发现凸显了在初级保健环境中制定整合抑郁症和心血管疾病管理的干预措施的重要性。