Department of Family Medicine and Community Health, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA.
Menopause. 2011 Dec;18(12):1298-302. doi: 10.1097/gme.0b013e31821f92f2.
The aim of this study was to examine the association between chronic medical conditions and reproducibility of self-reported age at menopause among community-dwelling women.
Age at menopause was assessed in a population-based longitudinal survey of 240 women twice, in 1993 and 2004. Women who recalled age at menopause in 2004 within 1 year or less of age at menopause recalled in 1993 (concordant) were compared with women who did not recall age at menopause in 2004 within 1 year of age at menopause recalled in 1993 (discordant). Type of menopause (surgical or natural) and chronic medical conditions were assessed by self-report.
One hundred forty-three women (59.6%) reported surgical menopause, and 97 (40.4%) reported natural menopause. In all, 130 (54.2%) women recalled age at menopause in 2004 within 1 year or less of recalled age at menopause in 1994, whereas 110 (45.8%) women did not recall age at menopause in 2004 within 1 year or less of recalled age at menopause in 1994. Among the women with surgical menopause, the women with three or more medical conditions were less likely to have concordant recall of age at menopause than the women with less than three chronic medical conditions (adjusted odds ratio, 0.36; 95% CI, 0.15-0.91) in multivariate models controlling for potentially influential characteristics including cognition and years since menopause.
Among women who underwent surgical menopause, the presence of three or more medical conditions is associated with decreased reproducibility of self-reported age at menopause.
本研究旨在探讨慢性疾病与社区居住女性自述绝经年龄再现性之间的关系。
对 240 名女性进行了一项基于人群的纵向调查，在 1993 年和 2004 年两次评估绝经年龄。在 2004 年回忆起的绝经年龄与 1993 年回忆起的绝经年龄相差 1 年或更短时间内（一致）的女性与在 1993 年回忆起的绝经年龄相差 1 年或更短时间内（不一致）未回忆起绝经年龄的女性进行比较。通过自我报告评估绝经类型（手术或自然）和慢性疾病。
143 名女性（59.6%）报告接受了手术性绝经，97 名女性（40.4%）报告自然绝经。共有 130 名女性（54.2%）在 2004 年回忆起的绝经年龄与 1994 年回忆起的绝经年龄相差 1 年或更短时间内，而 110 名女性（45.8%）在 2004 年回忆起的绝经年龄与 1994 年回忆起的绝经年龄相差 1 年或更短时间内未回忆起绝经年龄。在接受手术性绝经的女性中，与慢性疾病少于三种的女性相比，患有三种或更多种疾病的女性绝经年龄再现性的可能性较小（调整后的优势比，0.36；95%置信区间，0.15-0.91），这些模型在多变量模型中控制了认知和绝经后年限等潜在影响因素。
在接受手术性绝经的女性中，存在三种或更多种疾病与自述绝经年龄的再现性降低有关。
