Paul D A, Locke R, Zook K, Leef K H, Stefano J L, Colmorgen G
Department of Pediatrics, Section of Neonatology, Christiana Care Health Services, Newark, DE 19718, USA.
J Perinatol. 2006 Feb;26(2):74-8. doi: 10.1038/sj.jp.7211428.
To determine whether there are any racial differences in the prenatal care of mothers delivering very low birth weight infants (VLBW).
Retrospective cohort study of infants cared for at a single regional level III neonatal intensive care unit over a 9-year period, July 1993-June 2002, N = 1234. The main outcome variables investigated included antenatal administration of steroids, delivery by cesarean section, and use of tocolytic medications. Both univariate and multivariate analyses were performed.
After controlling for potential confounding variables, white mothers delivering VLBWs had an increased odds of cesarean delivery (odds ratio 1.5, 95% confidence intervals (CI) 1.1-2.0), receiving antenatal steroids (1.3, CI 1.01-1.8), and tocolysis (1.4, CI 1.1-2.0) compared to black mothers. The models controlled for gestational age, multiple gestation, premature labor, clinical chorioamnionitis, maternal age, income, year of birth, and presentation.
In our population of VLBWs, white mothers are more likely to receive antenatal steroids, tocolytic medications, and deliver by cesarean section when compared to black mothers. From our data we cannot determine the reasons behind these racial differences in care of mothers delivering VLBWs.
确定分娩极低出生体重儿(VLBW)的母亲在产前护理方面是否存在种族差异。
对1993年7月至2002年6月期间在单一地区三级新生儿重症监护病房接受护理的婴儿进行回顾性队列研究,N = 1234。所调查的主要结局变量包括产前使用类固醇、剖宫产分娩以及使用宫缩抑制剂。进行了单变量和多变量分析。
在控制了潜在的混杂变量后,与黑人母亲相比,分娩VLBW的白人母亲剖宫产分娩的几率增加(优势比1.5,95%置信区间(CI)1.1 - 2.0),接受产前类固醇治疗的几率增加(1.3,CI 1.01 - 1.8),使用宫缩抑制剂的几率增加(1.4,CI 1.1 - 2.0)。模型控制了胎龄、多胎妊娠、早产、临床绒毛膜羊膜炎、产妇年龄、收入、出生年份和胎位。
在我们的VLBW人群中,与黑人母亲相比,白人母亲更有可能接受产前类固醇治疗、使用宫缩抑制剂并通过剖宫产分娩。根据我们的数据,我们无法确定这些在分娩VLBW母亲护理方面的种族差异背后的原因。