Liu Yuanhong, Gao Hongjun
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, People's Republic of China.
Org Lett. 2006 Jan 19;8(2):309-11. doi: 10.1021/ol052706+.
[reaction: see text] The coupling reactions of alpha-alkynylated zirconacyclopentene based on 1,4-bis(trimethylsilyl)-1,3-butadiyne with unsaturated compounds are described, which provide an efficient, regio- and stereocontrollable synthesis of trans-enediynes in a one-pot procedure. An interesting alkynyl group shift from alpha- to beta-position of the zirconium center during the reaction was observed, which was accountable for the novel transformations to trans-enediynes.
[反应：见正文] 描述了基于1,4-双（三甲基硅基）-1,3-丁二炔的α-炔基化锆环戊烯与不饱和化合物的偶联反应，该反应在一锅法中提供了一种高效、区域和立体可控的反式烯二炔合成方法。在反应过程中观察到一个有趣的炔基从锆中心的α位转移到β位，这解释了向反式烯二炔的新型转化。
