Riccio C, Scognamiglio R
Istituto di Clinica Odontoiatrica e Stomatologica, I Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II.
Minerva Stomatol. 1992 Jan-Feb;41(1-2):13-21.
The authors, thanks to the application of monoclonal antibodies, as well as the immunohistochemical technique of APAAP, have traced the qualitative and quantitative features of inflammatory cells implied in periapical lesions. Moreover ten patients, of whom 6 males and 4 females aged between 20 and 60 have been tested. The immunohistochemical reactions revealed a heterogeneous population of B and T (T4-T8) lymphocytes, together with myeloid trunk cells (granulocytes and histiocytes). The B lymphocytes form nearly 31.5% of all the inflammatory cell, whereas the T types form about 55.8. The granulo-histiocyte part implies 11.1% of all the inflammatory cells themselves. The average percentages of the roted inflammatory cells have been compared with two diagnostic categories of periapical granuloma and periapical cyst. However, by comparing the obtained results with the ones described by other authors, we notice agreement as for as qualitative analysis is concerned, while as for quantitative analysis, some differences are proved. Finally, this situation shows that the quantitative demonstration of inflammatory cell populations is only a moment in the development of immune reactions in the inflammatory tissue.
作者们通过应用单克隆抗体以及APAAP免疫组织化学技术，追踪了根尖周病变中炎症细胞的定性和定量特征。此外，对10名患者进行了检测，其中6名男性和4名女性，年龄在20至60岁之间。免疫组织化学反应显示存在异质性的B和T（T4 - T8）淋巴细胞群体，以及髓系干细胞（粒细胞和组织细胞）。B淋巴细胞占所有炎症细胞的近31.5%，而T细胞类型约占55.8%。粒细胞 - 组织细胞部分占所有炎症细胞的11.1%。已将分类炎症细胞的平均百分比与根尖周肉芽肿和根尖周囊肿的两种诊断类别进行了比较。然而，通过将所得结果与其他作者描述的结果进行比较，我们发现在定性分析方面存在一致性，而在定量分析方面，存在一些差异。最后，这种情况表明炎症细胞群体的定量证明只是炎症组织中免疫反应发展过程中的一个阶段。
