Hayes Edward B, Gubler Duane J
Division of Vector-Borne Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado 80522, USA.
Annu Rev Med. 2006;57:181-94. doi: 10.1146/annurev.med.57.121304.131418.
West Nile virus (WNV) was first detected in North America in 1999 during an outbreak of encephalitis in New York City. Since then the virus has spread across North America and into Canada, Latin America, and the Caribbean. The largest epidemics of neuroinvasive WNV disease ever reported occurred in the United States in 2002 and 2003. This paper reviews new information on the epidemiology and clinical aspects of WNV disease derived from greatly expanded surveillance and research on WNV during the past six years.
西尼罗河病毒（WNV）于1999年在纽约市脑炎疫情期间首次在北美被发现。自那时起，该病毒已蔓延至北美全境，并扩散到加拿大、拉丁美洲和加勒比地区。有记录以来最大规模的西尼罗河病毒神经侵袭性疾病疫情于2002年和2003年在美国发生。本文回顾了过去六年中通过对西尼罗河病毒进行大幅扩展的监测和研究而获得的有关该病毒疾病流行病学和临床方面的新信息。
