Feltbower R G, Campbell F M, Bodansky H J, Stephenson C R, McKinney P A
Paediatric Epidemiology Group, Centre for Epidemiology and Biostatistics, University of Leeds and Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Diabet Med. 2006 Jan;23(1):86-9. doi: 10.1111/j.1464-5491.2005.01763.x.
Primary Care Trusts (PCTs) are now responsible for the planning and delivery of health-care services throughout England and Wales. As the 25 PCTs throughout Yorkshire are representative of the national distribution in terms of population structure and socio-economic status, we aimed to address the paucity of information describing the burden of childhood diabetes in primary care and to evaluate the cost implications of insulin pump therapy on individual PCTs.
We extracted information from a population-based register in Yorkshire, including 1952 patients diagnosed under the age of 15 years from 1990 to 2003. Each patient's postcode was linked to an individual PCT. Incidence rates (per 100 000 patient years) were derived and assessed for evidence of heterogeneity across PCTs and within Strategic Health Authorities (SHAs).
Incidence rates were lower in West Yorkshire (19.1, 95% CI 18.0-20.2) than North-east Yorkshire (20.3, 18.9-21.6), although this difference was not significant (P = 0.20). No significant evidence of heterogeneity in incidence rates was observed across PCTs (P = 0.46). Ninety per cent of all PCTs would expect four to seven newly diagnosed children per year, corresponding to a single general practitioner (GP) referring an individual for diagnosis once every 15 years on average. Assuming 1% of current patients under the age of 15 years with diabetes were to move onto insulin pump therapy, this would impose an additional cost of pound400-1300 per year for each PCT. The average cost was 15% lower for PCTs in West Yorkshire than North and East Yorkshire.
The additional resources required to pay for insulin pump therapy for a small proportion of the diabetes population would be minimal given the potential benefits to these patients of improved control and anticipated reduction in long-term morbidity.
初级保健信托基金(PCTs)现负责英格兰和威尔士各地医疗服务的规划与提供。鉴于约克郡的25个初级保健信托基金在人口结构和社会经济地位方面代表了全国分布情况,我们旨在解决初级保健中关于儿童糖尿病负担的信息匮乏问题,并评估胰岛素泵治疗对各初级保健信托基金的成本影响。
我们从约克郡的一个基于人群的登记册中提取信息,其中包括1990年至2003年期间诊断出的1952名15岁以下患者。每个患者的邮政编码与一个单独的初级保健信托基金相关联。得出发病率(每10万个患者年),并评估各初级保健信托基金之间以及战略卫生当局(SHAs)内部的异质性证据。
西约克郡的发病率(19.1,95%可信区间18.0 - 20.2)低于东北约克郡(20.3,18.9 - 21.6),尽管这种差异不显著(P = 0.20)。在各初级保健信托基金之间未观察到发病率异质性的显著证据(P = 0.46)。所有初级保健信托基金中有90%预计每年有4至7名新诊断的儿童,这相当于一名全科医生平均每15年转诊一人进行诊断。假设目前15岁以下糖尿病患者中有1%转而接受胰岛素泵治疗,这将使每个初级保健信托基金每年产生400 - 1300英镑的额外成本。西约克郡初级保健信托基金的平均成本比北部和东部约克郡低15%。
鉴于胰岛素泵治疗对一小部分糖尿病患者改善控制和预期降低长期发病率有潜在益处,为这部分患者支付胰岛素泵治疗所需的额外资源将是极少的。